Avneet Saini, Ph.D.
Peptides & Nanoconjugates Translational Research Lab
I'm an Associate Professor in the Department of Biophysics, Panjab University, Chandigarh (India).
We work on the development and biovalidation of small synthetic peptides and their nanoconjugates for diverse applications ranging from therapeutics to Biomaterials and even Diagnostics. Our work also includes synthesis of functional nanomaterials that act as antifouling agents and active biomaterials that find utility in wound healing and medical implant coatings along with other material applications.
Research Interests
The underlying theme of our research is the Design and Structural Characterization of novel peptides/peptidomimetics to solve the challenges posed by existing molecules and the use of a range of Computational Biology, Molecular Biophysics and Biophysical Chemistry Techniques to analyze these macromolecules and their interactions with the target.
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We also work on the development of peptide-based nanomaterials. Modifying abiotic nano surfaces with active biomolecules such as peptides extends the potential applications of nanomaterials in various fields by improving their biocompatibility and biorecognition abilities, thereby greatly enhancing their biosensing performances in terms of both selectivity and sensitivity. These biomaterials are also being investigated for their potential applications as medical implant coatings, wound healing, and other material applications.
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Many of our projects are directed towards biological problems of therapeutic and diagnostic relevance, and we have an extensive network of interdisciplinary collaborations within Panjab University and other institutions nationally and internationally.
Patent Granted
Recent Publications
Barman, P., Sharma, S., Joshi, S., Maan, M., Sharma, S., Saini, A., 2025. Design, characterization, and validation of a high-affinity synthetic peptide as bioreceptor for label-free detection of prostate specific antigen. Spectrochim Acta A Biomol Spectrosc., 15: 343: 126531. DOI: 10.1016/j.saa.2025.126531
Joshi, S., Maan, M., Barman, P., Sharely, I., Verma, K., Preet, S., and Saini., A. 2025. Advances in Biomaterials for Wound Care Management: Insights from Recent Developments. Advances in Colloid and Interface Science, 343:103563. doi: 10.1016/j.cis.2025.103563
Joshi, S., Barman, P., Maan, M., Goyal, H., Sharma, S., Kumar, R., ... & Saini, A. 2024. Development of a two-dimensional peptide functionalized-reduced graphene oxide biomaterial for wound care applications. Nanoscale, Volume 16, 20986-21001 https://doi.org/10.1039/D4NR02233E
Get in Touch
Department of Biophysics,
Basic Medical Science Block-2 (BMS Block-2), South Campus, Panjab University, Sec-25
Chandigarh-160014 (India)