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Publications

  • Saini, Sandeep, Rathore, Aayushi, Sharma, Sheetal, Saini, A., 2024. Exploratory data analysis of physicochemical parameters of natural antimicrobial and anticancer peptides: Unraveling the patterns and trends for the rational design of novel peptides. Bioimpacts 14(1):26438-26438. https://bi.tbzmed.ac.ir/Article/bi-26438.

  • Barman, P., Sharma, C., Joshi, S., Sharma, S., Maan, M., Rishi, P., Singla, N., Saini, A. 2023 In Vivo Acute Toxicity and Therapeutic Potential of a Synthetic Peptide, DP1 in a Staphylococcus aureus Infected Murine Wound Excision Model. Probiotics & Antimicro. Prot. 5:22:31 Z. https://doi.org/10.1007/s12602-023-10176-1.

  • Barman, P., Joshi, S., Sharma, S., Preet, S., Sharma, S. and Saini, A., 2023. Strategic Approaches to Improvise Peptide Drugs as Next Generation Therapeutics. International Journal of Peptide Research and Therapeutics, 29(4), p.61. DOI: https://doi.org/10.1007/s10989-023-10524-3.

  • Bhardwaj, A., Bhardwaj, R., Saini, A., Dhawan, D. K., & Kaur, T., 2023. Impact of calcium influx on endoplasmic reticulum in Excitotoxic neurons: role of chemical chaperone 4-PBA. Cellular and Molecular Neurobiology, 43(4), 1619-1635. DOI: https://doi.org/10.1007/s10571-022-01271-y.

  • Sheetal Sharma, Hemant Goyal, Shubhi Joshi, Bimla Nehru, Avneet Saini, Molecular interactions of resveratrol with Aβ 42 peptide and fibril during in-vitro Aβ 42 aggregation, Advances in Redox Research, Volume 7, 2023, 100060, ISSN 2667-1379, https://doi.org/10.1016/j.arres.2023.100060.

  • Saini S, Khurana S, Saini D, Rajput S, Thakur CJ, Singh J, Jaswal A, Kapoor Y, Kumar V, Saini A. In silico analysis of genomic landscape of SARS-CoV-2 and its variant of concerns (Delta and Omicron) reveals changes in the coding potential of miRNAs and their target genes. Gene. 2023 Feb 15;853:147097. DOI: 10.1016/j.gene.2022.147097.

  • Sharma, P., Sharma, S., Joshi, S., Barman P., Bhatt A., Maan M., Singla N., Rishi P., Ali Md. E., Preet S., Saini A.,  Design, characterization and structure–function analysis of novel antimicrobial peptides based on the N-terminal CATH-2 fragment. Sci Rep 12, 12058 (2022). https://doi.org/10.1038/s41598-022-16303-2.

  • Sharma S., Barman P., Joshi S., Preet S., Saini A., Multidrug resistance crisis during COVID-19 pandemic: Role of anti-microbial peptides as next-generation therapeutics. Colloids and Surfaces B: Biointerfaces (2022), 211:112303, https://doi.org/10.1016/j.colsurfb.2021.112303.

  • Kumar R.J., Jaswal R.R., Saini A., Dhawan D.K., Chadha V.D., Chemoinformatic Study and in vitro Bioevaluation of Tc-99m-Labeled N-Acetyl Neuraminic Acid in C6 Glioma Cells: Potential Role as a Radionuclide Imaging Probe. Indain Journal of Nuclear Medicine (2021); 36:267-72. https://doi.org/10.4103/ijnm.ijnm_5_21.

  • Sharma S., Saini A., Nehru B., Neuroprotective effects of carbenoxolone against amyloid-beta 1–42 oligomer-induced neuroinflammation and cognitive decline in rats. NeuroToxicology, (2021) 83, 89-105, ISSN 0161-813X,  https://doi.org/10.1016/j.neuro.2020.12.015.

  • Chauhan S., Dhawan D.K., Saini A., Preet S. Antimicrobial Peptides against Colorectal Cancer-a Focused Review. Pharmacological Research, (2021). 105529, ISSN 1043-6618. https://doi.org/10.1016/j.phrs.2021.105529.

  • Joshi, S., Singh, H., Sharma, S., P. Barman, A. Saini, G. Verma. Synthesis and characterization of graphene oxide-bovine serum albumin conjugate membrane for adsorptive removal of Cobalt(II) from water. Int. J. Environ. Sci. Technol. (2021). https://doi.org/10.1007/s13762-020-03050-y.

  • Radhika Rani, Reetika Sahore, Avneet Saini, Exploraing the chemical space of Tubulin and various binding pockets: A docking and computational study. Pb. Univ. Res. Journal (Sci), (2020); 71: 51-63.

  • Joshi S, Siddiqui R, Sharma P, Kumar R, Verma G, Saini A. Green synthesis of peptide functionalized reduced graphene oxide (rGO) nano bioconjugate with enhanced antibacterial activity. Scientific Reports. (2020);10:9441. http://doi.org/10.1038/s41598-020-66230-3.

  • Saini S, Saini A, Thakur CJ, Kumar V, Gupta RD, Sharma J. Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity. Molecular Biology Research Communications. (2020); 9 (2): 83-91. http://doi.org/10.22099/MBRC.2020.36507.1487.

  • Sharma S, Saini R, Sharma P, Saini A, Nehru B. Maintenance of Amyloid-beta Homeostasis by Carbenoxolone Post Aβ-42 Oligomer Injection in Rat Brain. Neuroscience. (2020);431:86-102. DOI: 10.1016/j.neuroscience.2020.02.004.

  • Joshi S, Sharma P, Siddiqui R, Kaushal K, Sharma S, Verma G, Saini A. A review on peptide functionalized graphene derivatives as nanotools for biosensing. Microchimica Acta. (2020);187(1):27. DOI: 10.1007/s00604-019-3989-1.

  • Parmar A, Barman P, Kaur G, Saini A, Sharma S. Biogenic Synthesis of Carbon-Based Micro Composites from Mushroom (Asparagus Disporus). Material Today: Proceedings. (2020);21:1862-7. DOI: 10.1016/j.matpr.2020.01.242.

  • Sharma S, Sharma N, Saini A, Nehru B, Carbenoxolone Reverses the Amyloid Beta 1-42 Oligomer-Induced Oxidative Damage and Anxiety-Related Behavior in Rats.  Neurotoxicity Research. (2019);35(3):654-667. DOI: 10.1007/s12640-018-9975-2.

  • Goyal D, Saini A, Saini GSS, Kumar R. Green synthesis of anisotropic gold nanoparticles using cinnamon with superior antibacterial activity. Materials Research Express. (2019);6(7):075043. DOI: 10.1088/2053-1591/ab15a6.

  • Preet S, Pandey SK, Kaur K, Chauhan S, Saini A. Gold nanoparticles assisted co-delivery of nisin and doxorubicin against murine skin cancer. Journal of Drug Delivery Science and Technology. (2019) ;53:101147.DOI: 10.1016/j.jddst.2019.101147.

  • Sharma S, Nehru B, Avneet Saini. Inhibition of Alzheimer’s amyloid-beta aggregation in-vitro by carbenoxolone: Insights into mechanism of action. Neurochemistry International. (2017);108:481-493. DOI: 10.1016/j.neuint.2017.06.011.

  • Sharma S, Verma S, Kapoor M, Saini A, Nehru B. Alzheimer’s disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior. Neurological Research. (2016);38 (9): 838-850. DOI: 10.1080/01616412.2016.120933

  • Saini A. Structural Modeling and Conformational Analysis of Aromatic Polypeptoid Models confined to different environmental conditions. International Journal of Computer Applications. (2016);143(7):46-56. DOI:10.5120/ijca2016910265

  • Saini A, Sharma S, Jaswal RR. Non-covalent interactions guide the structural plasticity of Desmin Tubulin binding peptides: A Molecular Mechanics and Molecular Dynamics Study. International Journal of Peptide Research and Therapeutics. (2015);21(4):459-478. DOI: 10.1007/s10989-015-9474-8.

  • Nandel FS, Jaswal RR, Saini A, Nandel V, Shafique M. Construction and conformational behavior of peptoids with cis-amide bond geometry: design of a peptoid with alternate φ, ψ values of inverse PP-II/PP-II and PP-I structures. Journal of Molecular Modeling. (2014);20:2429. DOI: 10.1007/s00894-014-2429-8.

  • Saini A, Jaswal RR, Negi R, Nandel FS. Insights on the structural characteristics of Vim-TBS (58-81) peptide for future applications as a cell penetrating peptide. BioScience Trends. (2013);7:209-220. DOI: 10.5582/bst.2013.v7.5.209.

  • Saini A, Bansal R. Insights on the Structural Characteristics of NDM I: The Journey so far. Advances in Biological Chemistry. 2012;3:323-334. DOI: 10.4236/abc.2012.24040.

  • Nandel FS and Saini A. Peptoids with aliphatic sidechains as helical structures without hydrogen bonds and collagen/ inverse-collagen type structures. Journal of Biophysical Chemistry. 2011;2:37-48. DOI:10.4236/jbpc.2011.21006.

  • Nandel FS and Saini A. Conformational Study of Short peptoid models for future applications as potent antimicrobial compounds. Macromolecular Theory and Simulations. 2007;16:295-303. DOI: 10.1002/mats.200600080

  • Nandel FS and Saini A. Construction and Design of Single Strand Collagen like Structure. Indian Journal of Biochemistry and Biophysics. 2007;44:106-113.

Book Chapters

  • Joshi S., Sharma S., Verma G., Saini A. Peptide functionalized nanomaterials as microbial sensors. In Photophysics and Nanophysics in Therapeutics (2022) by Elsevier Inc. ISBN: 978-0-323-89839-3.

  • Barman P., Sharma S., Saini A. Improving the functionality of a nanomaterial by biological probes. In Photophysics and Nanophysics in Therapeutics (2022) by Elsevier Inc. ISBN: 978-0-323-89839-3.

  • Sharma S, Joshi S, Sharma P, Barman P, Jyoti, Saini A. As a wonderful sensing material, Isothiocyanate based detection of chemical agents. In Spectrum of Isothiocyanate Chemistry & its Applications (2021) by Nova Science Publishers. ISBN: 978-1-53616-478-7.

  • Jaswal RR, Kaushal K, Joshi S, Sharma P, Sharma S, Preet S, Saini A. Exploring the Potential of peptides and peptidomimetics in Biosensing. In Strategies to Overcome Superbug Invasions: Emerging Research and Opportunities. IGI Global (2021). ISBN10:1799803074, ISBN13:9781799803072. DOI: 10.4018/978-1-7998-0307-2.ch003

  • Tripathi R, Sharma P, Saini A, Verma G. Self-healed Materials from Elastomeric Composites: Concepts, Strategies and Developments. In Smart Polymer Nanocomposites (2017) Pg 219-242. Springer International Publishing. Print ISBN: 978-3-319-50423-0, Electronic ISBN: 978-3-319-50424-7. https://doi.org/10.1007/978-3-319-50424-7_8

  • Saini A and Verma G. “Peptoids: Tomorrow’s Therapeutics”. In Nanostructures for Novel Therapy: Synthesis, Characterization and Applications. (2017). Chapter 10, Pg 251-280. Elsevier Publications. ISBN: 978-0-323-46142-9. https://doi.org/10.1016/B978-0-323-46142-9.00010-4.

Edited Book

  • Photophysics and Nanophysics in Therapeutics. (2022) Edited by Nilesh M. Mahajan, Avneet Saini, Nishikant A. Raut, Sanjay J. Dhoble. Published by Elsevier Inc. ISBN: 978-0-323-89839-3. 

Patents

  • Peptide and Device for the detection of Prostate Specific Antigen. Avneet Saini,   Panchali Barman, Sheetal Sharma, Shweta Sharma. Indian Patent Office, Application No.202211061821 A, 4 Nov 2022.

  • Process and development of nano-bio composite anti-bacterial additive for commercial paint production. Gaurav Verma, Avneet Saini, Shubhi Joshi, Deeksha Sharma. Indian Patent Office, Application No. 202211011934 A, 4 March 2022.

  • A Synthetic Peptide Possessing Antimicrobial and Anticancer Properties. Avneet Saini, Pratibha Sharma, Simran Preet, Neha Singla, Praveen Rishi. Indian Patent Office, Application No. 202011015631, 9 April 2020.

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