Avneet Saini, Ph.D.
Peptide Design and Characterization Group
I'm an Assistant Professor in the Department of Biophysics, Panjab University, Chandigarh (India).
We work on designing artificial peptides for various applications ranging from therapeutics to Diagnostics. Our work also includes the development of peptide nanomaterials that function as biomaterials and find utility in wound healing and medical implant coatings along with other material applications.
Research Interests
The underlying theme of our research is the Design and Structural Characterization of novel peptides/peptidomimetics to solve the challenges posed by existing molecules and the use of a range of Computational Biology, Molecular Biophysics and Biophysical Chemistry Techniques to analyze these macromolecules and their interactions with the target.
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We also work on the development of peptide-based nanomaterials. Modifying abiotic nano surfaces with active biomolecules such as peptides extends the potential applications of nanomaterials in various fields by improving their biocompatibility and biorecognition abilities, thereby greatly enhancing their biosensing performances in terms of both selectivity and sensitivity. These biomaterials are also being investigated for their potential applications as medical implant coatings, wound healing, and other material applications.
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Many of our projects are directed towards biological problems of therapeutic and diagnostic relevance, and we have an extensive network of interdisciplinary collaborations within Panjab University and other institutions nationally and internationally.
Patent Granted
Recent Publications
Shubhi Joshi, Jatin Chadha, Kusum Harjai, Gaurav Verma, Avneet Saini, 2024. Synthetic peptide (DP1) functionalized graphene oxide: A biocompatible nanoformulation with broad-spectrum antibacterial and antibiofilm activity. FlatChem, Volume 44, 100626, ISSN 2452-2627, https://doi.org/10.1016/j.flatc.2024.100626.
Mayank Maan, Hemant Goyal, Shubhi Joshi, Panchali Barman, Sheetal Sharma, Rajesh Kumar, Avneet Saini, 2024. DP1, a multifaceted synthetic peptide: Mechanism of action, activity and clinical potential, Life Sciences, 340:122458. https://doi.org/10.1016/j.lfs.2024.122458.
Saini, Sandeep, Rathore, Aayushi, Sharma, Sheetal, Saini, A., 2024. Exploratory data analysis of physicochemical parameters of natural antimicrobial and anticancer peptides: Unraveling the patterns and trends for the rational design of novel peptides. Bioimpacts 14(1):26438-26438. https://bi.tbzmed.ac.ir/Article/bi-26438.
Get in Touch
Department of Biophysics,
Basic Medical Science Block-2 (BMS Block-2), South Campus, Panjab University, Sec-25
Chandigarh-160014 (India)